Wu Yuan


We developed a super-achromatic flexible probe with an ultracompact form factor (approximately 520 micrometers in outer diameter), enabling ultrahigh-resolution (approximately 1.7 micrometers axial resolution (in tissue)) endoscopic optical coherence tomography imaging at 800 nanometers.

This technology affords a great potential to perform “optical biopsies” without the need for tissue removal or processing. It has significant translational potential for in vivo clinical applications in assessing tissue pathological changes in internal luminal organs, particularly those of small and/or young subjects and complex internal organs (such as small airways). I am doing my research in the Biophotonics Imaging Technology Lab directed by Xingde Li at the Department of Biomedical Engineering.

Questions & Answers

Why did you choose Johns Hopkins for your work?

With its world-class clinical practice and biomedical research, Johns Hopkins is an ideal place to tackle real-world clinical challenges with innovative technologies.

What contributed to your project’s success? (Special skills, interests, opportunities, guidance, etc.)

Guidance and encouragement from my mentor and help from my talented colleagues all contributed to the success of this work.

What thoughts do you have about Young Investigators’ Day itself, as a celebration of the roles students and fellows play in research at Johns Hopkins?

Young Investigators’ Day provides a very important stage for recognizing and encouraging students and fellows for their great contributions to research excellence at Johns Hopkins.

What has been your best/most memorable experience while at Johns Hopkins?

Working and collaborating with medical doctors and technical experts at Johns Hopkins has been immensely rewarding.

Tell us something interesting about yourself.

I enjoy playing soccer, running and swimming. And I enjoy my time with my kids.